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Research Article

Efficacy of 200 IU OnabotulinumtoxinA (Botulinum Toxin Type A) in Patients with Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment: A Retrospective Analysis


1 Department of Urology, Ataşehir Memorial Hospital, Istanbul, Türkiye
2 Department of Urology, Üsküdar University, Faculty of Medicine, Istanbul, Türkiye
3 Department of Urology, Private İskenderun Gelişim Hospital, Hatay, Türkiye


DOI : 10.33719/nju1550632
New J Urol. 2025;20(2):64-70.

Abstract

Objective: The aim of this study is to retro-spectively examine the data of 112 patients who had laparoscopic transperitoneal pyeloplasty (LTPP) or laparoscopic retroperitoneal pyeloplasty (LRPP) operations at our clinic due to primary ureteropel-vic junction obstruction.

Material and Methods: The data from patients who had standard laparoscopic pyeloplasty between January 2007 and January 2015 with a primary UPJ obstruction were examined. Comparative data from transperitoneal and retroperitoneal laparoscopic approaches were statistically analyzed.

Results: Given the demographic and clini-cal characteristics of the patients (74 patients with transperitoneal, 38 patients with retroperitoneal surgery), there were no significant differences be-tween the two groups. Mean operation duration was 149.52 minutes in the transperitoneal approach and 187.76 minutes in the retroperitoneal approach. In-tracorporeal suturing was 66.4 minutes on average in the transperitoneal approach and 84.21 minutes in the retroperitoneal approach. The visual ana-logue scores, which were evaluated on postopera-tive days 1 and 2, the need for analgesics, and the length of stay in hospital were found to be higher in the group with LTPP compared to the LRPP group. One patient in each group had to undergo conver-sion to open surgery.


Abstract

Objective: The aim of this study is to retro-spectively examine the data of 112 patients who had laparoscopic transperitoneal pyeloplasty (LTPP) or laparoscopic retroperitoneal pyeloplasty (LRPP) operations at our clinic due to primary ureteropel-vic junction obstruction.

Material and Methods: The data from patients who had standard laparoscopic pyeloplasty between January 2007 and January 2015 with a primary UPJ obstruction were examined. Comparative data from transperitoneal and retroperitoneal laparoscopic approaches were statistically analyzed.

Results: Given the demographic and clini-cal characteristics of the patients (74 patients with transperitoneal, 38 patients with retroperitoneal surgery), there were no significant differences be-tween the two groups. Mean operation duration was 149.52 minutes in the transperitoneal approach and 187.76 minutes in the retroperitoneal approach. In-tracorporeal suturing was 66.4 minutes on average in the transperitoneal approach and 84.21 minutes in the retroperitoneal approach. The visual ana-logue scores, which were evaluated on postopera-tive days 1 and 2, the need for analgesics, and the length of stay in hospital were found to be higher in the group with LTPP compared to the LRPP group. One patient in each group had to undergo conver-sion to open surgery.