Objective: Primitive neuroectodermal tu-mors (PNET) of the kidney are very rare tu-mors with aggressive behavior. They usually are associated with poor prognosis.
Case: A 26-year old male patient presented to our clinic with right flank pain, microscopic hematuria and moderate-heavy nausea com-plaints. CT imaging studies showed a tumor with 17x13x18 cm dimensions. A mass excision was not possible caused by tumor spread to liv-er surface and duodenum and the tumor could not be separated from these surfaces. The op-eration was finished with an excisional biopsy.
The patient received 7 cycles of alternating IE/VAC chemotherapy sessions. At 5th month of follow-up, PET-CT scans showed that the tumor was regressed to 8x6x7 cm dimensions. Following this outcome, radical nephrectomy was performed without risking any other or-gans.
Conclusion: Neoadjuvant chemotherapy can be employed prior to radical nephrectomy in such cases in order to radically/efficiently/drastically reduce the tumor mass
Key Words: neuroectodermal tumor, kid-ney, neoadjuvant chemotherapy
Abstract
Objective: Primitive neuroectodermal tu-mors (PNET) of the kidney are very rare tu-mors with aggressive behavior. They usually are associated with poor prognosis.
Case: A 26-year old male patient presented to our clinic with right flank pain, microscopic hematuria and moderate-heavy nausea com-plaints. CT imaging studies showed a tumor with 17x13x18 cm dimensions. A mass excision was not possible caused by tumor spread to liv-er surface and duodenum and the tumor could not be separated from these surfaces. The op-eration was finished with an excisional biopsy.
The patient received 7 cycles of alternating IE/VAC chemotherapy sessions. At 5th month of follow-up, PET-CT scans showed that the tumor was regressed to 8x6x7 cm dimensions. Following this outcome, radical nephrectomy was performed without risking any other or-gans.
Conclusion: Neoadjuvant chemotherapy can be employed prior to radical nephrectomy in such cases in order to radically/efficiently/drastically reduce the tumor mass
Key Words: neuroectodermal tumor, kid-ney, neoadjuvant chemotherapy