Purpose: To investigate the effect of age on oncologic and survival results in patients under-going radical cystectomy due to muscle invasive bladder cancer.
Material and Method: We reviewed the data of 178 patients who underwent radical cystectomy between January 2006 and Novem-ber 2016 due to bladder cancer in our clinic. Finally 147 patients who underwent radical cystectomy due to muscle-invasive bladder can-cer were included in the study. Patients were di-vided into two groups as; patient age ≤ 70 years (Group 1) and > 70 years (Group 2). Then we compared the groups in terms of preoperative data, oncological outcomes and survival fin-dings.
Results: There were 101 and 46 patients in group 1 and group 2 respectively. There was no statistically significant difference between the two groups in terms of gender, preoperative T stage, tumor grade, preoperative hydronephro-sis and precence of carcinoma in situ (CIS). Pre-operative ASA score was higher in the elderly group (Group 2) (p = 0.007). Postoperative data showed that the presence of variant histology, T stage, upstaging, tumor grade, lymph node metastasis, positive surgical margins were simi-lar between the two groups. There was no sta-tistically significant difference between the two groups in terms of overall survival and cancer-specific survival.
Conclusion : There was no statistically sig-nificant difference between oncologic and survi-val findings between ≤ 70 years and > 70 years old patients who underwent radical cystectomy due to muscle invasive bladder cancer.
Keywords: bladder cancer; age; radical cystectomy
Abstract
Purpose: To investigate the effect of age on oncologic and survival results in patients under-going radical cystectomy due to muscle invasive bladder cancer.
Material and Method: We reviewed the data of 178 patients who underwent radical cystectomy between January 2006 and Novem-ber 2016 due to bladder cancer in our clinic. Finally 147 patients who underwent radical cystectomy due to muscle-invasive bladder can-cer were included in the study. Patients were di-vided into two groups as; patient age ≤ 70 years (Group 1) and > 70 years (Group 2). Then we compared the groups in terms of preoperative data, oncological outcomes and survival fin-dings.
Results: There were 101 and 46 patients in group 1 and group 2 respectively. There was no statistically significant difference between the two groups in terms of gender, preoperative T stage, tumor grade, preoperative hydronephro-sis and precence of carcinoma in situ (CIS). Pre-operative ASA score was higher in the elderly group (Group 2) (p = 0.007). Postoperative data showed that the presence of variant histology, T stage, upstaging, tumor grade, lymph node metastasis, positive surgical margins were simi-lar between the two groups. There was no sta-tistically significant difference between the two groups in terms of overall survival and cancer-specific survival.
Conclusion : There was no statistically sig-nificant difference between oncologic and survi-val findings between ≤ 70 years and > 70 years old patients who underwent radical cystectomy due to muscle invasive bladder cancer.
Keywords: bladder cancer; age; radical cystectomy