Purpose: To evaluate the effect of tamsulosin 0.4 mg and silodosin 8 mg for the medical expulsive treatment in distal ureteral stones.
Material and Methods: Between January 2014 and December 2015, 184 patients with acute renal colic who were diagnosed as distal ureteral stone (4 to 9 mm) by computarized tomography were evaluated retrospectively. Patients were divided into three groups: first group (follow-up group) (n=59) took dexketoprofen 25 mg on-demand, second group (tamsulosin group) (n=64) took tamsulosin 0.4 mg daily and dexketoprofen 25 mg on-demand, third group (silodosin group) (n=61) took silodosin 8 mg daily and dexketoprofen 25 mg on-demand. All patients were observed for 4 weeks. Stone expul-sion rates, expulsion time, need for analgesics and adverse events were recorded.
Results: Stone expulsion rates were 63% in the follow-up group, 77% in the tamsulosin group and, 82% in the silodosin group. Need for analge-sics, pain episodes, expulsion time were higher in follow-up group than the other two groups. No seri-ous adverse events was recorded.
Conclusion: Medical expulsive treatment is an option for uncomplicated distal ureteral stones. A statistically significant increase in the stone expul-sion rate and reduction for use of analgesics can be achieved with tamsulosin 0.4 mg and silodosin 8 mg in patients with distal ureteral stones.
Keywords: Medical expulsive treatment, alfa blocker, ureteral stone
Abstract
Purpose: To evaluate the effect of tamsulosin 0.4 mg and silodosin 8 mg for the medical expulsive treatment in distal ureteral stones.
Material and Methods: Between January 2014 and December 2015, 184 patients with acute renal colic who were diagnosed as distal ureteral stone (4 to 9 mm) by computarized tomography were evaluated retrospectively. Patients were divided into three groups: first group (follow-up group) (n=59) took dexketoprofen 25 mg on-demand, second group (tamsulosin group) (n=64) took tamsulosin 0.4 mg daily and dexketoprofen 25 mg on-demand, third group (silodosin group) (n=61) took silodosin 8 mg daily and dexketoprofen 25 mg on-demand. All patients were observed for 4 weeks. Stone expul-sion rates, expulsion time, need for analgesics and adverse events were recorded.
Results: Stone expulsion rates were 63% in the follow-up group, 77% in the tamsulosin group and, 82% in the silodosin group. Need for analge-sics, pain episodes, expulsion time were higher in follow-up group than the other two groups. No seri-ous adverse events was recorded.
Conclusion: Medical expulsive treatment is an option for uncomplicated distal ureteral stones. A statistically significant increase in the stone expul-sion rate and reduction for use of analgesics can be achieved with tamsulosin 0.4 mg and silodosin 8 mg in patients with distal ureteral stones.
Keywords: Medical expulsive treatment, alfa blocker, ureteral stone