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Research Article

Efficacy of 200 IU OnabotulinumtoxinA (Botulinum Toxin Type A) in Patients with Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment: A Retrospective Analysis


1 Department of Urology, Ataşehir Memorial Hospital, Istanbul, Türkiye
2 Department of Urology, Üsküdar University, Faculty of Medicine, Istanbul, Türkiye
3 Department of Urology, Private İskenderun Gelişim Hospital, Hatay, Türkiye


DOI : 10.33719/nju1550632
New J Urol. 2025;20(2):64-70.

Abstract

Ischemia-reperfusion injury in tissues lea-ving temporary or permanent damage patients’ health is closely related to the clinical situation. Free oxygen radicals plays an important role in the pathophysiology of ischemia-reperfusion injury. Hydroxyl ion is the most powerful free radical. Reducing hydrogen and hydroxyl ions selectively and with different tissue protective mechanisms makes preventive effect on ischa-emia-reperfusion injury. Today, hydrogen is a powerful antioxidant that is done much research on the tissue protective effect. This study evalua-ted the clinical reflection of hydrogen is used in urologic diseases and their effects on the future were discussed.

Key Words: Antioxidant, Hydrogen, Uro-logy


Abstract

Ischemia-reperfusion injury in tissues lea-ving temporary or permanent damage patients’ health is closely related to the clinical situation. Free oxygen radicals plays an important role in the pathophysiology of ischemia-reperfusion injury. Hydroxyl ion is the most powerful free radical. Reducing hydrogen and hydroxyl ions selectively and with different tissue protective mechanisms makes preventive effect on ischa-emia-reperfusion injury. Today, hydrogen is a powerful antioxidant that is done much research on the tissue protective effect. This study evalua-ted the clinical reflection of hydrogen is used in urologic diseases and their effects on the future were discussed.

Key Words: Antioxidant, Hydrogen, Uro-logy